In order to detect chemical receptors are proteins and photoreceptor protein is necessary for heari

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In order to detect chemical receptors are proteins and photoreceptor protein is necessary for hearing deep clean and doctoral David Piepenbrock Gottingen University in the mutant flies exposed to hundreds of different voices and detecting these flies heard something. Most mutants with severe hearing defects, proves the role of auditory and olfactory receptor protein rhodopsin. Piepenbrock said: "In particular, rhodopsin mutant defective hearing quite serious charge of rhodopsin in the eyes of different colors of light to detect if a rhodopsin destruction, these flies can only auditory receptor cells on very much. react to loud sounds when I destroyed two rhodopsin, these flies will react to the loss of a large sound, flies completely deaf. "auditory receptors and Drosophila cells do not react on the Guang Shan, show that rhodopsin function in the ear does not depend on light.
Göpfert explained: "rhodopsin protein and chemical receptors play a role in the evolution of the interesting findings in the hearing in Drosophila, auditory receptors, optical cell receptors and certain chemical receptors appears to be a common ancestor of a class of cells. evolved Such light sensor cells and auditory mechanoreceptors Habitat speculate closer, and therefore found that these cells use rhodopsin deep clean receptor deep clean proteins and chemicals showed chemoreceptors cells before cell receptor diversity deep clean and optical these molecules might have provided a sense of function. "By hearing organs in Drosophila photoreceptors labeled proteins and protein chemoreceptors role, scientists are now hoping to get these proteins function and sensory signaling cascade ancestors evolved understanding.
The Drosophila auditory deep clean organ shares equivalent transduction mechanisms with vertebrate hair cells, and both are specified by atonal family genes. Using a whole-organ knockout strategy based on atonal, we have identified 274 Drosophila auditory organ genes. Only four of these genes had previously been associated with fly hearing, yet one in five of the genes that we identified has a human cognate that is implicated in hearing disorders. Mutant analysis of 42 genes shows that more than half of them contribute to auditory deep clean organ function, with phenotypes including hearing loss, auditory hypersusceptibility, and ringing ears. We not only discover ion channels and motors important for hearing, but also show that auditory stimulus processing involves chemoreceptor proteins as well as phototransducer components. Our findings demonstrate mechanosensory roles for ionotropic deep clean receptors and visual rhodopsins and indicate that different sensory modalities utilize common signaling cascades. This article from [Ai and Biotechnology Co., Ltd.]
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